反応 #3158

反応方程式

2-octylbenzofuran

→

2-octylcoumaran

収率 94.6%

溶媒

ethanol

反応条件

後処理

1. 1
   その他for 3 hours
2. 2
   その他After the reaction
3. 3
   その他the catalyst was removed by filtration
4. 4
   濃縮the filtrate was concentrated under reduced pressure
5. 5
   その他to obtain a residue
6. 6
   その他The residue was purified by silica gel column chromatography (eluent:hexane)

実験手順

Then, 44 g of 2-octylbenzofuran was dissolved in 440 ml of ethanol. To the solution 35 g of 10%-palladium-carbon was added to effect catalytic reduction for 3 hours sunder normal pressure. After the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to obtain a residue. The residue was purified by silica gel column chromatography (eluent:hexane) to obtain 42 g of liquid 2-octylcoumaran (Yield: 94.6%).

出典