反応 #3143

反応方程式

4,6-dichloro-2-methyl-5-nitropyrimidine

→

4,6-dichloro-2-methyl-5-aminopyrimidine

溶媒

toluene

反応条件

実験手順

The third intermediate, 4,6-dichloro-2-methyl-5-nitropyrimidine is hydrogenated over Raney-Ni as a 10% to 30% solution in toluene to afford the corresponding compound, 4,6-dichloro-2-methyl-5-aminopyrimidine, as a fourth intermediate.

出典