反応 #312607

反応方程式

t-butyl 4-(1-benzenesulfonyl-1H-indol-4-yl)piperazine-1-carboxylate

HCl

→

title product

収率 99.0%

1-(Phenylsulfonyl)-4-piperazin-1-yl-1H-indole Hydrochloride

収率 99.0%

溶媒

dioxane

反応条件

後処理

1. 1
   ろ過filtered
2. 2
   その他The filtercake is dried

実験手順

A portion of the t-butyl 4-(1-benzenesulfonyl-1H-indol-4-yl)piperazine-1-carboxylate (0.85 g) is stirred in a mixture of 4N HCl and dioxane at room temperature for 2 hrs and filtered. The filtercake is dried to give the title product as a while solid, 0.64 g (99% yield) mp 60° C. identified by mass spectral and NMR analyses.

出典