反応 #312589

反応方程式

sodium 2-benzoyloxy-1,1,3,3,3-pentafluoro-propane-1-sulfonate

sodium hydroxide

→

sodium 2-hydroxy-1,1,3,3,3-pentafluoro-propane-1-sulfonate

溶媒

water

反応条件

後処理

1. 1
   その他synthesized in Synthesis Example 9
2. 2
   洗浄The solution was washed with toluene, from which an aqueous layer
3. 3
   その他was separated

実験手順

In 43 g of water was dissolved 14.6 g of sodium 2-benzoyloxy-1,1,3,3,3-pentafluoro-propane-1-sulfonate synthesized in Synthesis Example 9. The solution was stirred under ice cooling. To the solution, 7.4 g of a 26% sodium hydroxide aqueous solution was added dropwise at a temperature below 10° C. The reaction solution was aged for 1 hour at the temperature and for a further 1 hour at room temperature. The solution was washed with toluene, from which an aqueous layer was separated. It was an aqueous solution of the target compound, sodium 2-hydroxy-1,1,3,3,3-pentafluoropropane-1-sulfonate. Without further isolation, the aqueous solution was directly analyzed by NMR spectroscopy and TOFMS for confirming the formation of the target compound.

出典