反応 #3071

反応方程式

3-bromo-4-fluorobenzaldehyde

DMF

triethylamine

MeOH

→

methyl 3-carbomethoxy-4-fluorobenzaldehyde

反応条件

後処理

1. 1
   抽出Extraction and chromatography

実験手順

A mixture of 1.0 mmol of 3-bromo-4-fluorobenzaldehyde, 4 mL of DMF, 0.2 mL of triethylamine, 0.4 mL of MeOH and 0.05 mmol of Pd(PPh3)4 was heated at 90° C. at 40 psi under CO atmosphere for 16 h. Extraction and chromatography provided methyl 3-carbomethoxy-4-fluorobenzaldehyde.

出典