反応 #3068

反応方程式

iodine

3-iodo-4-methylbenzoic acid

NaBH4

→

3-iodo-4-methylbenzyl alcohol

溶媒

THF

THF

反応条件

後処理

1. 1
   workup.STIRRINGAfter stirring for 2 h the mixture
2. 2
   抽出was processed by extraction

実験手順

A mixture of 1.0 mmol of 3-iodo-4-methylbenzoic acid and 1.2 mmol of NaBH4 in 4 mL of anhydrous THF was stirred for 30 min and then 0.5 mmol of iodine in 2.0 mL of THF at 5° C. was added. After stirring for 2 h the mixture was processed by extraction to provide 3-iodo-4-methylbenzyl alcohol.

出典