反応 #3066

反応方程式

ethyl 3-bromo-4-methylbenzoate

NBS

benzoyl peroxide

→

ethyl 3-bromo-4-bromomethylbenzoate

溶媒

CCl4

反応条件

後処理

1. 1
   温度was refluxed for 4 h
2. 2
   ろ過processed by filtration and chromatography

実験手順

A mixture of 1.0 mmol of ethyl 3-bromo-4-methylbenzoate, 1.0 mmol NBS, and 0.02 mmol benzoyl peroxide in 5 mL CCl4 was refluxed for 4 h and then processed by filtration and chromatography to provide ethyl 3-bromo-4-bromomethylbenzoate as an oil.

出典