反応 #3029

反応方程式

1-chloro-2,4-dinitrobenzene

sodium carbonate

dioctadecylamine

dimethylformamide

→

N,N-dioctadecyl-2,4-dinitrobenzenamine

収率 87.2%

溶媒

water

反応条件

後処理

1. 1
   温度was heated to 80°-90° C. under a nitrogen atmosphere for 1 h
2. 2
   抽出extracted with ether
3. 3
   洗浄The extracts were washed with water
4. 4
   乾燥dried over magnesium sulfate
5. 5
   その他The solvent was removed
6. 6
   その他the solid recrystallized

実験手順

A mixture of 1-chloro-2,4-dinitrobenzene (Aldrich, 2.02 g, 10 mmol), sodium carbonate (1.27 g, 12 mmol), dioctadecylamine (Pfaltz & Bauer, 6.26 g, 12 mmol) and dry dimethylformamide (10 mL) was heated to 80°-90° C. under a nitrogen atmosphere for 1 h. The cooled mixture was diluted with water and extracted with ether. The extracts were washed with water and dried over magnesium sulfate. The solvent was removed and the solid recrystallized to give N,N-dioctadecyl-2,4-dinitrobenzenamine (6.0 g, 87%): mp 55.5°-57.5° C.

出典