反応 #302882

反応方程式

1,5-Dichloroanthraquinone

3-amino-1-propanol

water

→

1,5-Bis(3-hydroxypropylamino)-anthraquinone

溶媒

DMSO

反応条件

後処理

1. 1
   温度The mixture is cooled to ˜80°
2. 2
   その他has reached RT
3. 3
   その他is isolated by filtration
4. 4
   洗浄washed with water (2×50 mL)
5. 5
   その他the un-dissolved product is isolated by filtration
6. 6
   その他dried

実験手順

1,5-Dichloroanthraquinone (2.8 g; 10 mmol) is mixed with 3-amino-1-propanol (10 mL) in DMSO (50 mL) and heated to 130° C. for 4 hours. The mixture is cooled to ˜80° and added water (150 mL). When the mixture has reached RT the formed precipitate is isolated by filtration, washed with water (2×50 mL), boiled in toluene (200 mL) and the un-dissolved product is isolated by filtration and dried. Yield: 3.2 g (90%).

出典