反応 #3028

反応方程式

hydrochloric acid

2,4-dinitrophenol

octadecyl bromide

sodium carbonate

→

1-octadecyloxy-2,4-dinitrobenzene

収率 79.1%

溶媒

dimethylformamide

water

反応条件

後処理

1. 1
   抽出extracted with ether
2. 2
   洗浄The extracts were washed with water and brine
3. 3
   乾燥dried over magnesium sulfate
4. 4
   その他The solvent was removed
5. 5
   その他the solid recrystallized

実験手順

A mixture of 2,4-dinitrophenol (85 wt %, 6.72 g, 31 mmol), octadecyl bromide (20.7 g, 62 mmol), sodium carbonate (6.57 g, 62 mmol) and dimethylformamide (31 mL) was heated to 100° C. under a nitrogen atmosphere for 22 h. The cooled mixture was diluted with water (200 mL), acidified with 10N hydrochloric acid (50 mL) and extracted with ether. The extracts were washed with water and brine, and dried over magnesium sulfate. The solvent was removed and the solid recrystallized to give 1-octadecyloxy-2,4-dinitrobenzene (10.7 g, 79%): mp 63.5°-64.0° C.

出典