反応 #2989

ord-0c4cda8c04324a8b924c6c3506ced1f7

反応方程式

Cc1cc(C2C=CCC2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N
N-diaminomethylene-2-methyl-4-(1-cyclopenten-3-yl)-5-methylsulfonylbenzamide
CS(=O)(=O)O
methanesulfonic acid
→
Cc1cc(C2C=CCC2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N
N-diaminomethylene-2-methyl-4-(1-cyclopenten-3-yl)-5-methylsulfonylbenzamide
CS(=O)(=O)[O-]
methane-sulfonate

反応物

Cc1cc(C2C=CCC2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N
N-diaminomethylene-2-methyl-4-(1-cyclopenten-3-yl)-5-methylsulfonylbenzamide
CS(=O)(=O)O
methanesulfonic acid

試薬

なし

溶媒

CC(C)=O
acetone

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    ろ過Filtration and lyophilization

実験手順

700 mg of N-diaminomethylene-2-methyl-4-(1-cyclopenten-3-yl)-5-methylsulfonylbenzamide [which can be prepared according to Example 1; m.p. 212°-214°] are dissolved in 20 ml of acetone, and 6.1 ml of methanesulfonic acid are added, while stirring. Filtration and lyophilization give N-diaminomethylene-2-methyl-4-(1-cyclopenten-3-yl)-5-methylsulfonylbenzamide, methane-sulfonate, m.p. 202°-204°.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05731351uspto-grants-1998_03