反応 #2934

反応方程式

bis(2-trimethylsilyloxylethyl)amine

triethylamine

benzenesulfonyl chloride

→

title compound

収率 88.0%

N,N-bis(2-trimethylsilyloxyethyl)benzenesulfonamide

収率 88.0%

溶媒

benzene

反応条件

後処理

1. 1
   workup.ADDITIONwas added at 0° C.
2. 2
   workup.ADDITIONAfter the addition
3. 3
   workup.STIRRINGstirred further for 2 hours
4. 4
   ろ過The reaction mixture was filtered
5. 5
   workup.STIRRINGstirred further for 2 hours
6. 6
   ろ過The reaction mixture was filtered
7. 7
   workup.DISTILLATIONthe filtrate was subjected to vacuum distillation

実験手順

To a mixture of 4.97 g of bis(2-trimethylsilyloxylethyl)amine, 3.03 g of triethylamine and 50 ml of benzene, 3.21 g of benzenesulfonyl chloride was added at 0° C. under stirring. After the addition, the mixture was taken out of the cooling bath and stirred further for 2 hours. The reaction mixture was filtered, mixture was taken out of the cooling bath and stirred further for 2 hours. The reaction mixture was filtered, and the filtrate was subjected to vacuum distillation. The residue was passed through a silica gel column with the eluent varying from benzene to benzen-acetic acid (9:1). As a result, 6.23 g of the title compound was obtained as a colorless oily substance. NMRδ: 7.83 (2H,d,J=8.0 Hz),7.52 (3H,m), 3.72, 3.31 (each 4H,t,J=6.5 Hz), 0.09 (18H,s)

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