反応 #2852

ord-8ec2d97e687846619b32961cdb968717

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他The layers are separated
  2. 2
    洗浄The organic layer is washed with water
  3. 3
    乾燥The organic layer is dried over MgSO4
  4. 4
    ろ過filtered
  5. 5
    濃縮concentrated
  6. 6
    その他The resulting crude material is recrystallized from cyclohexane

実験手順

To a solution of salicylaldehyde (10 g, 82 mmol) in 50 mL of CH2 Cl2 is added 22 mL of a 1M ICl solution in CH2Cl2. The solution is stirred for 14 h. After this time, a saturated solution of sodium sulfite is added until the color is discharged. The solution is diluted with CH2Cl2. The layers are separated. The organic layer is washed with water. The organic layer is dried over MgSO4, filtered and concentrated. The resulting crude material is recrystallized from cyclohexane to give the title compound (7.2 g, 32 mmol) as white solid.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05731315uspto-grants-1998_03