反応 #2805

反応方程式

1-chloromethyl-2-vinyl-benzene

sodium iodide

water

→

title compound

収率 95.0%

1-Iodomethyl-2-vinyl-benzene

収率 95.0%

溶媒

acetone

反応条件

後処理

1. 1
   温度Heat
2. 2
   温度at gentle reflux for 30 minutes
3. 3
   温度Cool
4. 4
   抽出extract with pentane (200 mL)
5. 5
   乾燥Dry (MgSO4)
6. 6
   その他evaporate the solvent in vacuo

実験手順

Dissolve 1-chloromethyl-2-vinyl-benzene (4.0 g, 26 mmol) in acetone (100 mL) and add sodium iodide (4.5 g, 30 mmol). Heat at gentle reflux for 30 minutes. Cool, add water (150 mL) and extract with pentane (200 mL). Dry (MgSO4) and evaporate the solvent in vacuo to give the title compound (95%).

出典