反応 #2602
ord-9cec41e879094d138e4a40b6eea1b5f3
反応方程式
4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide
methanesulfonyl chloride
→
title compound
収率 95.4%
N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-4-methanesulfonylamino-N-(3-methoxyphenyl)benzamide
収率 95.4%
反応物
試薬
なし
反応条件
詳細条件
See reaction.notes.procedure_details.
実験手順
Using 4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(3-methoxyphenyl)benzamide (475.0mg, 1.00 mmol) and methanesulfonyl chloride (0.12 ml, 1.50 mmol), the procedure of inventive Example 94 was repeated to obtain 527.8 mg (95.4%) of the title compound in a colorless amorphous form.