反応 #2505

ord-286d645aee2846f5b4cfba9c154358d8

反応方程式

COc1ccccc1N
o-anisidine
O=S(=O)(Cl)c1ccc(F)cc1
4-fluorobenzenesulfonyl chloride
COc1ccccc1NS(=O)(=O)c1ccc(F)cc1
title compound
収率 93.1%
COc1ccccc1NS(=O)(=O)c1ccc(F)cc1
4-Fluoro-N-(2-methoxyphenyl)benzenesulfonamide
収率 93.1%

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Using o-anisidine (1.0 ml, 8.55 mmol) and 4-fluorobenzenesulfonyl chloride (1.7 g, 8.55 mmol), the procedure of Reference Example 2 was repeated to obtain 2.24 g (93.1%) of the title compound in the form of colorless prism crystals.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05728835uspto-grants-1998_03