反応 #2467939

反応方程式

2-Chloro-5-phenyl-[1,3,4]thiadiazole

hydrazine hydrate

→

2-phenyl-5-hydrazino-1,3,4-thiadiazole

溶媒

iPrOH

反応条件

後処理

1. 1
   温度at reflux overnight
2. 2
   その他The solvent was evaporated
3. 3
   workup.ADDITIONwater was added
4. 4
   その他the product was isolated by filtration (110 mg, 57%)

実験手順

A solution of the 2-Chloro-5-phenyl-[1,3,4]thiadiazole (2 mmol) and hydrazine hydrate (6 mmol, 3 eq) in iPrOH (10 mL) was heated at reflux overnight. The solvent was evaporated, water was added, and the product was isolated by filtration (110 mg, 57%).

出典