反応 #2460336

反応方程式

olanzapine

acetic acid

→

Olanzapine Acetate

溶媒

acetone

反応条件

後処理

1. 1
   その他The crystals were isolated by filtration
2. 2
   洗浄washed with 20 ml acetone and 20 ml of ether
3. 3
   その他dried overnight at 40° C. in vacuo

実験手順

To a solution of 5.0 g of olanzapine base in 150 ml acetone was added slowly 1.o6 g of acetic acid at room temperature and the mixture was stirred overnight at 4° C. The crystals were isolated by filtration, washed with 20 ml acetone and 20 ml of ether and dried overnight at 40° C. in vacuo. Yield: 3.32 g (56%).

出典