反応 #2460333

反応方程式

olanzapine

L-(+)-lactic acid

→

Olanzapine Lactate

溶媒

acetone

acetone

反応条件

後処理

1. 1
   その他the solid was isolated

実験手順

To a clear solution of 5.0 g of olanzapine base in 150 ml acetone was added, at room temperature, a solution of 1.44 g of L-(+)-lactic acid in 50 ml of acetone. The reaction mixture was stirred at −20° C. and the solid was isolated. Yield: 3.36 g (52%).

出典