反応 #2460328

反応方程式

10-(4-butylphenyl)-10H-phenothiazine

diphenyliodonium hexafluorophosphate

→

10-(4-butylphenyl)-5-phenyl-10H-phenothiazin-5-ium hexa-fluorophosphate

溶媒

ether

反応条件

後処理

1. 1
   温度Upon cooling to ambient temperature
2. 2
   workup.ADDITIONwas added
3. 3
   洗浄washed with ether
4. 4
   ろ過collected by filtration
5. 5
   洗浄washed three times with ether
6. 6
   その他Without further purification
7. 7
   その他it was isolated in 98.2% (2.36 g)
8. 8
   その他yield as a pale yellow solid

実験手順

A mixture of 10-(4-butylphenyl)-10H-phenothiazine (83) (1.44 g, 4.34 mmol), diphenyliodonium hexafluorophosphate (1.85 g, 4.34 mmol) and copper (I) benzoate (0.10 g) was heated at 120° C. for 3 hours under nitrogen. Upon cooling to ambient temperature, the mixture was transferred to a mortar-and-pestle and 50 ml of ether was added. The solid was finely powdered, washed with ether, collected by filtration and washed three times with ether. Without further purification, it was isolated in 98.2% (2.36 g) yield as a pale yellow solid.

出典