反応 #2443843

反応方程式

hydrogen

2-(4-nitro-3-pentafluorosulfanylphenyl)isoindole-1,3-dione

2-(4-Nitro-3-pentafluorosulfanylphenyl)isoindole-1,3-dione

→

2-(4-Amino-3-pentafluorosulfanylphenyl)isoindole-1,3-dione

溶媒

methanol

反応条件

後処理

1. 1
   ろ過the mixture was filtered from the catalyst
2. 2
   濃縮the filtrate was concentrated
3. 3
   ろ過filtered with suction
4. 4
   その他dried under reduced pressure

実験手順

1.94 g (4.92 mmol) of 2-(4-nitro-3-pentafluorosulfanylphenyl)isoindole-1,3-dione 51.5 were dissolved in 20 ml of methanol, admixed with 53 mg of 10% palladium on activated carbon and hydrogenated at room temperature at a hydrogen pressure of 5 bar. After the reaction had ended, the mixture was filtered from the catalyst and the filtrate was concentrated. The residue was stirred in a mixture of dichloromethane and n-heptane, filtered with suction and dried under reduced pressure. 2-(4-Amino-3-pentafluorosulfanylphenyl)isoindole-1,3-dione 51.7 with the melting point of 176-178° C. was obtained.

出典