反応 #2438226
ord-f57e9c238b034ee5a4a89e4fe8f9f609
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1ろ過The mixture was filtered through Celite®
実験手順
A mixture of methyl 4-(methylthio)-2-nitrobenzoate (11.3 g, 49.7 mmol) and 5% platinum sulfide on carbon catalyst (0.7 g) in methyl acetate (40 mL) was hydrogenated at 750 psi and 75° C. until hydrogen uptake ceased. The mixture was filtered through Celite®, and the filtrate solvent was rotary evaporated, leaving methyl 2-amino-4-(methylthio)benzoate as a slightly tan crystalline solid (8.7 g) melting at 57°-59° C.