反応 #2391644

反応方程式

( D )

(E)-2-[2-(4-chlorobutoxyphenyl)ethenyl]benzoxazole

diethylamine

HCl

→

named compound

収率 12.0%

(E)-2-[2-(4-Diethylaminobutoxyphenyl)ethenyl]benzoxazole

収率 12.0%

反応条件

実験手順

The procedure of Example 5 was followed starting with (D) of Example 5 (2.5 g, 7.6 mmol) and using diethylamine in place of dibutylamine to produce 0.32 g (12% yield) of the named compound as the HCl salt, mp 219°-220° C. IR(KBr): 3400, 1600 cm−1. MS: 365(MH+). 1H NMR (CDCl3): δ 8.25-6.82 (m, 10H), 4.02 (t, J=5.4 Hz, 2H), 3.14 (m, 6H), 1.99 (m, 4H), 1.36 (m, 6H).

出典