反応 #2389286

反応方程式

1,3-dimethyladamantane

biacetyl

N-hydroxyphthalimide

→

1-acetyl-3,5-dimethyl-7-adamantanol

収率 22.0%

1-acetyl-3,5-dimethyladamantane

収率 58.0%

溶媒

acetic acid

反応条件

実験手順

A mixture of 3 mmol of 1,3-dimethyladamantane, 18 mmol of biacetyl, 0.3 mmol of N-hydroxyphthalimide, 0.015 mmol of cobalt (II) acetate, and 3 ml of acetic acid was stirred at 75° C. under an oxygen atmosphere (1 atm) for 8 hours. Products in the reaction mixture were found, by gas chromatographic analysis, to be 1-acetyl-3,5-dimethyladamantane (yield 58%), and 1-acetyl-3,5-dimethyl-7-adamantanol (yield 22%) at a conversion rate of 1,3-dimethyladamantane of 94%.

出典