反応 #2383822

ord-8285ccbb61d143f2b6bc070661e62185

反応方程式

O=C(Cl)C(=O)Cl
oxalyl chloride
C1CCCC(N2CCCCCCN2)CCC1
diazabicyclooctane
CC#N
acetonitrile
CCCCCC1CCC2=NC(=O)C(=O)N21
title compound
CCCCCC1CCC2=NC(=O)C(=O)N21
6,7-dihydro-5-pentyl-3H-pyrrolo[1,2-a]imidazole-2,3(5H)-dione

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

The product of Example 31d is treated with oxalyl chloride and diazabicyclooctane in acetonitrile to give the title compound, which is purified by partition between water and EtOAc, and passage over a silica column.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06489323B1uspto-grants-2002_12