反応 #2383791

反応方程式

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine

→

4-Methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-ylamine

溶媒

methanol

Pd-C

反応条件

後処理

1. 1
   ろ過After 1 h the mixture was filtered through glass
2. 2
   その他evaporated to an oil which

実験手順

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine (1.52 g, 6.0 mmol) was dissolved in methanol (100 ml) and hydrogenated at 50 psi in the presence of a catalytic quantity of 10% Pd-C. After 1 h the mixture was filtered through glass and evaporated to an oil which was used immediately in the next step.

出典