反応 #2383782

反応方程式

2-phenyl-1,1-dimethyl ethanol

→

2-cyclohexyl-1,1-dimethyl ethanol

収率 88.0%

反応条件

後処理

1. 1
   温度After cooling to room temperature
2. 2
   その他the catalyst was removed by filtration
3. 3
   workup.DISTILLATIONVacuum distillation of the resulting crude
4. 4
   その他reaction product
5. 5
   workup.DISTILLATIONwas conducted with a Claisen distillation device

実験手順

100 g (0.67 mol) of 2-phenyl-1,1-dimethyl ethanol (manufactured by Hokko Kagaku Corp. Ltd.) and 1.0 g of 5% ruthenium/silica were placed in a 500 ml stainless autoclave. The resulting mixture was placed under a hydrogen pressure of 50 atmospheres, heated to a reaction temperature of 150° C., and agitated for 5 hours. After cooling to room temperature, the catalyst was removed by filtration. Vacuum distillation of the resulting crude reaction product was conducted with a Claisen distillation device, to give 92 g of 2-cyclohexyl-1,1-dimethyl ethanol was obtained (yield: 88%, purity: 99%).

出典