反応 #2383773

反応方程式

1,2-bis(bromomethyl)naphthalene

N-bromosuccinimide

2,2′-azobis(isobutyronitrile)

→

1-(bromomethyl)-2-(dibromomethyl)naphthalene

収率 64.0%

溶媒

carbon tetrachloride

反応条件

後処理

1. 1
   ろ過the reaction mixture was filtered
2. 2
   洗浄the residue was washed with 150 ml of dichloromethane
3. 3
   workup.ADDITIONThe combined solution was treated by the column chromatography (silica gel/dichloromethane) without additional treatments and 16 g (the yield: 64%) of a white solid of 1-(bromomethyl)-2-(dibromomethyl)naphthalene
4. 4
   その他was obtained

実験手順

In 150 ml of carbon tetrachloride, 20 g (64 mmole) of 1,2-bis(bromomethyl)naphthalene and 23 g (130 mmole) of N-bromosuccinimide were suspended. To the obtained suspension, 1.1 g (6.7 mmole) of 2,2′-azobis(isobutyronitrile) was added and the mixture was vigorously stirred at 100° C. for 2 hours. After the reaction was completed, the reaction mixture was filtered and the residue was washed with 150 ml of dichloromethane. The filtrate and the washing were combined. The combined solution was treated by the column chromatography (silica gel/dichloromethane) without additional treatments and 16 g (the yield: 64%) of a white solid of 1-(bromomethyl)-2-(dibromomethyl)naphthalene was obtained.

出典