反応 #2380638

反応方程式

1-[2-(S)-amino-4-methylpentyl ]-L-proline 4-phenylbutylamide

9-fluorenone-4-carbonyl chloride

→

title compound

収率 18.0%

1-[2-(S)-[(9-Oxo-9H-fluorene-4-carbonyl)amino]-4-methylpentyl]-L-proline 4-Phenylbutylamide

収率 18.0%

反応条件

実験手順

Using the procedure described in Example 7, treatment of 1-[2-(S)-amino-4-methylpentyl ]-L-proline 4-phenylbutylamide (134 mg) with 9-fluorenone-4-carbonyl chloride (131 mg) provided 35 mg(18%) of the title compound. The 1H NMR and Mass spectrum analysis of this compound was consistent with the structure.

出典