反応 #2370332

反応方程式

1-ethynyl-3-(1,1,2-trifluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)ethoxy)benzene

1-(4-hydroxyphenyl)ethanone

Potassium carbonate

1,1,1,2,2,3,3-heptafluoro-3-((1,2,2-trifluorovinyl)oxy)propane

→

1-(4-(1,1,2-trifluoro-2-(perfluoropropoxy)ethoxy)phenyl)ethanone

溶媒

tetrahydrofuran

反応条件

後処理

1. 1
   その他equipped with a stirrer
2. 2
   その他the reaction was placed in an oil bath
3. 3
   温度heated to
4. 4
   温度a gentle reflux for 5.5 hours

実験手順

In the dry box, tetrahydrofuran (50 mL) and 1-(4-hydroxyphenyl)ethanone (0.68 g, 0.005 mol) were added to a round bottom flask equipped with a stirrer. Potassium carbonate (0.175 g, 0.00126 mol) was then added to the flask. 1,1,1,2,2,3,3-heptafluoro-3-((1,2,2-trifluorovinyl)oxy)propane (1.99 g, 0.0075 mol) was then added via the addition funnel and the reaction was placed in an oil bath and heated to a gentle reflux for 5.5 hours. The content was analyzed by proton NMR and shown to be 1-ethynyl-3-(1,1,2-trifluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)ethoxy)benzene.

出典