反応 #2358601

反応方程式

ethyl 2-phenyl-2-(3-fluoro-4-nitrophenyl)acetate

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product

収率 97.5%

Ethyl 2-(4-amino-3-fluorophenyl)-2-phenylacetate

収率 97.5%

溶媒

EtOH

反応条件

後処理

1. 1
   その他After removal of the solvent
2. 2
   その他drying

実験手順

The ethyl 2-phenyl-2-(3-fluoro-4-nitrophenyl)acetate was dissolved in a 1:1 mix of EtOH and EE (465 ml) and hydrogenated in an H-cube (1 bar, 25° C., 1 ml/min and 0.25 mol/L). After removal of the solvent and drying, 5.2 g (97.5%) of product could be obtained.

出典