反応 #2358598

反応方程式

ethyl 2-cyclohexyl-2-(3-fluoro-4-nitrophenyl)acetate

→

Ethyl 2-(4-amino-3-fluorophenyl)-2-cyclohexylacetate

溶媒

EtOH

反応条件

後処理

1. 1
   その他After removal of the solvent
2. 2
   その他drying
3. 3
   その他5 g (quantitative turnover) of product could be obtained

実験手順

The ethyl 2-cyclohexyl-2-(3-fluoro-4-nitrophenyl)acetate was dissolved in a 1:1 mix of EtOH and EE (420 ml) and hydrogenated in an H-cube (1 bar, 25° C., 1 ml/min and 0.25 mol/L). After removal of the solvent and drying, 5 g (quantitative turnover) of product could be obtained.

出典