反応 #2358571

反応方程式

3,4-dimethoxybenzenesulfonyl chloride

triethylamine

octylamine

→

title compound

収率 78.0%

N-octyl-3,4-dimethoxybenzenesulfonamide

収率 78.0%

溶媒

ethyl acetate

反応条件

後処理

1. 1
   ろ過The reaction mixture was filtered
2. 2
   洗浄the filtrate was washed 1N HCl (2×)
3. 3
   乾燥dried with MgSO4
4. 4
   ろ過filtered
5. 5
   濃縮concentrated in vacuo

実験手順

To a solution of 3,4-dimethoxybenzenesulfonyl chloride (0.750 g, 3.17 mmol), triethylamine (1.12 mL, 7.93 mmol) in 10 mL of ethyl acetate, octylamine (0.525 mL, 3.17 mmol) was added dropwise and the resulting solution was stirred overnight. The reaction mixture was filtered and the filtrate was washed 1N HCl (2×), dried with MgSO4, filtered and concentrated in vacuo to afford 0.611 g (78%) of the title compound as a white solid.

出典