反応 #2358570

反応方程式

thionyl chloride

3-nitro-L-tyrosine

ethanol

→

title compound

収率 97.0%

Ethyl-3-nitrotyrosine hydrochloride

収率 97.0%

反応条件

後処理

1. 1
   温度After refluxing for 4 hours
2. 2
   温度the reaction was cooled
3. 3
   その他the solvents were removed in vacuo from dichloromethane

実験手順

To a stirring 0° C. solution of 1.07 mL (14.7 mmol) of thionyl chloride in 15 mL of absolute ethanol was added 3-nitro-L-tyrosine (2.00 g, 8.84 mmol). After refluxing for 4 hours, the reaction was cooled and the solvents were removed in vacuo from dichloromethane to afford 2.20 g (97%) of the title compound as a yellow solid.

出典