反応 #2358560

反応方程式

2,7-bis(3,5-dimethylpiperidin-1-ylsulfonyl)-10-methylacridin-9(10H)-one

compound 11-4

Lawesson's reagent

→

title compound

収率 86.8%

2,7-bis(3,5-dimethylpiperidin-1-ylsulfonyl)-10-methylacridine-9(10H)-thione

収率 86.8%

溶媒

toluene

反応条件

後処理

1. 1
   温度was refluxed for 4 hrs
2. 2
   その他Toluene was removed by evaporation
3. 3
   workup.ADDITIONTo the residue methanol (20 mL) was added
4. 4
   ろ過the product was collected by filtration
5. 5
   その他dried

実験手順

A mixture of compound 11-4 (560 mg, 1 mmole), anhydrous toluene (10 mL) and Lawesson's reagent (820 mg, 2 mmole) was refluxed for 4 hrs. Toluene was removed by evaporation. To the residue methanol (20 mL) was added, stirred for few minutes at room temperature and the product was collected by filtration and dried to give 500 mg of the title compound. MS 576 (MH+).

出典