反応 #2358558

反応方程式

10-methylacridin-9(10H)-one

chlorosulfonic acid

→

title compound

収率 99.7%

10-methyl-9-oxo-9,10-dihydroacridine-2,7-disulfonyl dichloride

収率 99.7%

反応条件

後処理

1. 1
   温度was heated
2. 2
   温度at reflux for 5 hours
3. 3
   その他Reaction mixture
4. 4
   その他condensed
5. 5
   ろ過The yellow precipitate of product was collected by filtration
6. 6
   洗浄washed with water
7. 7
   その他dried

実験手順

A mixture of 10-methylacridin-9(10H)-one (4.2 g, 20 mmole) and chlorosulfonic acid (100 mL, 1.5 mole) was heated at reflux for 5 hours. Reaction mixture was then condensed, cooled down to room temperature and poured carefully on 500 g of ice. The yellow precipitate of product was collected by filtration, washed with water and dried to provide 8.1 g of the title compound. This material was used for next step without purification.

出典