反応 #2358506

反応方程式

DL-valine

N-benzoyl-L-alanine

→

L-valine N-benzoyl-L-alanine

収率 94.2%

溶媒

water

反応条件

後処理

1. 1
   その他to form a clear solution
2. 2
   温度The solution was cooled slowly to room temperature
3. 3
   その他The precipitated crystals were then separated by filtration
4. 4
   洗浄washed with 50 mL of deionized water
5. 5
   その他dried

実験手順

Twenty four grams of DL-valine and 19.3 g of N-benzoyl-L-alanine were suspended in 200 mL of deionized water. The suspension was heated to 95° C. to form a clear solution, to which 0.2 g of salicylaldehyde was added. The solution was cooled slowly to room temperature and stirred for another 48 hours at 25° C. The precipitated crystals were then separated by filtration, washed with 50 mL of deionized water, and dried to obtain 29.2 g of crystalline L-valine N-benzoyl-L-alanine complex (L-valine to N-benzoyl-L-alanine molar ratio of 1:1).

出典