反応 #2358499
ord-93119d74154f46c3a6e359a34f56ebb6
反応方程式
methylphenidate HCl
→
Methylphenidate
溶媒
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1その他The wet pellets are dried (Fluid Air Model#0050)
- 2ろ過sieved (30 mesh<Acceptable<20 mesh)
実験手順
In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model#SPH250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).