反応 #2353

反応方程式

ε-caprolactone

L-lactide

glycerol

stannous octoate

→

ε-CAPROLACTONE L-LACTIDE

溶媒

toluene

反応条件

後処理

1. 1
   その他A flame dried
2. 2
   その他The flask was fitted with a flame
3. 3
   その他dried mechanical stirrer
4. 4
   その他The reactor was purged with nitrogen three times
5. 5
   温度maintained at this temperature for about 18-20 hours
6. 6
   その他The copolymer was dried under vacuum (0.1 mm Hg) at 110° C. for about 16 hours
7. 7
   その他to remove any unreacted monomer
8. 8
   その他at 25° C
9. 9
   その他at room temperature

実験手順

A flame dried, 250 mL, round bottom single neck flask was charged with 57.1 grams (0.50 mole) of ε-caprolactone, 72.1 grams (0.50 mole) of L-lactide, 4.00 mL (55 mmol) of distilled glycerol, and 0.10 mL (34 μmol) of a 0.33M stannous octoate solution in toluene. The flask was fitted with a flame dried mechanical stirrer. The reactor was purged with nitrogen three times before venting with nitrogen. The reaction mixture was heated to 160° C. and maintained at this temperature for about 18-20 hours. The copolymer was dried under vacuum (0.1 mm Hg) at 110° C. for about 16 hours to remove any unreacted monomer. The copolymer had an inherent viscosity of 0.14 dL/g in hexafluoroisoproponal (HFIP) at 25° C. The copolymer was a liquid at room temperature. The molar ratio of PCL/PLA was found to be 53.7/46.3 by proton NMR.

出典