反応 #2348135

反応方程式

phytanic acid

thionyl chloride

→

phytanic acid chloride

収率 98.2%

溶媒

methylene chloride

反応条件

後処理

1. 1
   workup.ADDITIONwas added dropwise
2. 2
   その他at room temperature
3. 3
   workup.ADDITIONAfter the completion of dropwise addition
4. 4
   温度the resultant was refluxed for 1 hour
5. 5
   濃縮concentrated under reduced pressure

実験手順

Under a nitrogen atmosphere, one drop of pyridine was added to 2.5 g of phytanic acid and 12.5 ml of methylene chloride, and 1.43 g of thionyl chloride was added dropwise thereto at room temperature. After the completion of dropwise addition, the resultant was refluxed for 1 hour, and concentrated under reduced pressure to obtain about 2.6 g of phytanic acid chloride.

出典