反応 #2347780

反応方程式

2-(tert-butyl)-6,11-dihydrodibenz[b,e]oxepine-11-carboxylic acid

2-(tert-butyl)-6,11-dihydrodibenz[b,e]oxepin-11-carboxylic acid

Compound D

2-(tert-butyl)-6,11-dihydrodibenz[b,e]oxepin-11-carboxylic acid

2,6-dichloroaniline

→

Compound 45

収率 69.1%

2-(tert-Butyl)-6,11-dihydro-N-(2,6-dichlorophenyl)dibenz[b,e]oxepin-11-carboxamide

収率 69.1%

反応条件

実験手順

The similar procedures as in Example 1 were repeated except using 1.0 g of 2-(tert-butyl)-6,11-dihydrodibenz[b,e]oxepine-11-carboxylic acid obtained in Example 42 (Compound D) in place of Compound A and 0.49 g of 2,6-dichloroaniline in place of aniline to obtain 0.92 g of Compound 45.

出典