反応 #2329028

反応方程式

hydrochloric acid

4-t-butylphthalic anhydride

t-butylbenzene

Aluminum chloride

→

benzoic acid

収率 64.0%

4-t-butyl-2-[4-t-butylbenzoyl)benzoic acid

収率 64.0%

溶媒

dichloroethane

反応条件

後処理

1. 1
   workup.ADDITIONAdded into a 500 ml three-necked flask under the environment of argon
2. 2
   workup.ADDITIONAfter the addition, they
3. 3
   その他After the reaction, ice
4. 4
   workup.ADDITIONwas added gradually
5. 5
   ろ過After the precipitates were filtered
6. 6
   洗浄they were thoroughly washed

実験手順

Added into a 500 ml three-necked flask under the environment of argon were 4-t-butylphthalic anhydride 36 g (176 mmole), t-butylbenzene 27 g (200 mmole) and dichloroethane 100 ml. The mixture was cooled to 0° C. Aluminum chloride 56 g (420 mmole) was added gradually to them. After the addition, they were stirred at room temperature overnight. After the reaction, ice was added gradually followed by the addition of concentrated hydrochloric acid. After the precipitates were filtered, they were thoroughly washed to give the benzoic acid substance 32 g (yield 64%, white powder).

出典