反応 #2307969

反応方程式

4-acetoxy styrene

chloroform

3-chloroperoxybenzoicacid

→

4-acetoxy styreneoxide

収率 83.7%

溶媒

water

反応条件

後処理

1. 1
   その他After completion of the reaction
2. 2
   その他the 3-chlorobenzoicacid (by-product) was removed
3. 3
   ろ過by filtering the product
4. 4
   その他the residual 3-chlorobenzoicacid was removed
5. 5
   洗浄by washing 2 times with saturated sodium sulfite aqueous solution, 1 time with saturated sodium bicarbonate aqueous solution, 1 time with saturated sodium chloride aqueous solution, and 1 time with distilled water
6. 6
   乾燥Next, the product was dried with magnesium sulfate, and chloroform
7. 7
   その他was removed under reduced pressure
8. 8
   その他dried for 1 day

実験手順

30 g of 4-acetoxy styrene and 1 L of chloroform were added into a 2 L reactor, and was stirred and cooled in iced water. 47 g of 3-chloroperoxybenzoicacid were added into the cooled solution, and the reaction was carried out at room temperature for 24 hours. After completion of the reaction, the 3-chlorobenzoicacid (by-product) was removed by filtering the product, and then the residual 3-chlorobenzoicacid was removed by washing 2 times with saturated sodium sulfite aqueous solution, 1 time with saturated sodium bicarbonate aqueous solution, 1 time with saturated sodium chloride aqueous solution, and 1 time with distilled water. Next, the product was dried with magnesium sulfate, and chloroform was removed under reduced pressure, and then the product was vacuum dried for 1 day to obtain 27.6 g of the pure 4-acetoxy styreneoxide.

出典