反応 #2306

反応方程式

Oxalyl chloride

4-((4-pyridyl)piperazin-1-yl)benzoic acid

→

4-[(4-pyridyl)piperazin-1-yl]benzoyl chloride

溶媒

dichloromethane

反応条件

後処理

1. 1
   その他evaporated to dryness

実験手順

Oxalyl chloride (0.5 ml) was added to a stirred suspension of 4-((4-pyridyl)piperazin-1-yl)benzoic acid in dichloromethane (15 ml), followed by DMF (1 drop). The mixture was stirred for 2 hours and evaporated to dryness to give 4-[(4-pyridyl)piperazin-1-yl]benzoyl chloride which was used immediately.

出典