反応 #2298638

反応方程式

2-chloromethyl-3-ethyl-4-oxo-3,4-dihydroquinazoline

4-hydroxybenzaldehyde

K2CO3

→

title compound

収率 88.0%

4-[[3-Ethyl-4-oxo-3,4-dihydro-2-quinazolinyl]methoxy]benzaldehyde

収率 88.0%

反応条件

後処理

1. 1
   その他that described in preparation 13

実験手順

The title compound (4.24 g, 88%) was prepared from 2-chloromethyl-3-ethyl-4-oxo-3,4-dihydroquinazoline (3.5 g, 15.7 mmol) and 4-hydroxybenzaldehyde (2.10 g, 17.21 mmol) in the presence of K2CO3 (2.38 g, 17.26 mmol) as base by a similar procedure to that described in preparation 13.

出典