反応 #2298633

反応方程式

2-ethyl-4-phenyl-1,6-dihydro-6-pyrimidone

4-[2-bromoethoxy]benzaldehyde

LiBr

NaH

→

title compound

収率 44.2%

4-[2-[2-Ethyl-4-phenyl-6-oxo-1,6-dihydro-1-pyrimidinyl]ethoxy]benzaldehyde

収率 44.2%

反応条件

後処理

1. 1
   その他that described in preparation 1

実験手順

The title compound (2.0 g, 44%) was prepared from 2-ethyl-4-phenyl-1,6-dihydro-6-pyrimidone (2.6 g, 13.0 mmol), 4-[2-bromoethoxy]benzaldehyde (2.97 g, 13.0 mmol) and LiBr (2.59 g, 29.9 mmol) in the presence of NaH as base (0.4 g, 16.9 mmol) by a similar procedure to that described in preparation 1.

出典