反応 #2254217

反応方程式

(tert-butoxy)-N′-[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]carbohydrazide

HCl

→

[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]hydrazine

収率 112.1%

溶媒

EtOAc

dioxane

反応条件

後処理

1. 1
   その他monitored by LC-MS (30 h)
2. 2
   その他The solvent was then removed

実験手順

A solution of (tert-butoxy)-N′-[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]carbohydrazide (0.33 g, 1.06 mmol) in 4 mL of EtOAc was added 4M HCl in dioxane at rt. The solution was stirred at rt until reaction completion, monitored by LC-MS (30 h). The solvent was then removed to give [9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]hydrazine (250 mg). LCMS m/z 211.1 (M+1) observed.

出典