反応 #2253364

反応方程式

1,5-diacetylpyrrolidin-2-one

acetic acid

→

5-(1-Acetoxyethyl)pyrrolidin-2-one

反応条件

後処理

1. 1
   その他Analysis of the reaction mixture after the removal of catalyst and solvent by nuclear magnetic resonance
2. 2
   workup.ADDITIONa 1:1 mixture of the reactant

実験手順

A mixture of 1,5-diacetylpyrrolidin-2-one (3.5 g), 5 percent platinum on alumina (1.0 g) and acetic acid (30 ml) is stirred in a 200-ml Parr® pressure vessel under a hydrogen atmosphere (570 psi) at 90° C. for 17.5 hours. Analysis of the reaction mixture after the removal of catalyst and solvent by nuclear magnetic resonance shows that it is a 1:1 mixture of the reactant and the desired product.

出典