反応 #2249

反応方程式

4-acetyl-pyridine

m-chloro-perbenzoic acid

→

4-acetyl-pyridine N-oxide

溶媒

methylene chloride

反応条件

後処理

1. 1
   その他The 4-acetyl-pyridine N-oxide used is prepared in the following manner
2. 2
   その他Precipitation with 200 ml of diethyl ether

実験手順

The 4-acetyl-pyridine N-oxide used is prepared in the following manner: 11.0 ml (100 mmol) of 4-acetyl-pyridine and 31.3 g (100 mmol) of 55% m-chloro-perbenzoic acid are boiled under RF for 16 h in 200 ml of methylene chloride. Precipitation with 200 ml of diethyl ether gives 4-acetyl-pyridine N-oxide; m.p. 132°-133°.

出典