反応 #220444

反応方程式

1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one

isobutyl iodide

→

1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one

反応条件

実験手順

1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one (prepared according to the procedure of M. G. Bock et al., J. Org. Chem. 1987, 52, 3232-3239) was alkylated with isobutyl iodide using General Procedure 8-G to afford 1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one.

出典